Illness title: Argyria
Affected populations: Though extra common in the 19th century due to heavy publicity to silver amongst individuals who labored with the metallic and the use of silver to treat diseases, argyria is now a rare condition. Consequently, there are restricted statistics on the true incidence of the illness. Nevertheless, one review of medical literature revealed as much as 2018 recognized 16 sufferers who developed argyria after publicity to a liquid suspension of silver, referred to as colloidal silver.
Causes: Argyria is attributable to the ingestion of — or exposure to — silver or silver-containing compounds. The silver accumulates within the physique and thus turns the skin and nails bluish-gray. The human physique usually comprises tiny quantities of silver from more minor exposures, equivalent to from meals and ingesting water. However in sufferers with argyria, these ranges have constructed up in extra over an extended time frame, starting from several months to years.
Individuals who work with silver or use colloidal silver as a dietary complement are at the greatest risk of developing argyria. This consists of individuals who eat colloidal silver as a type of different drugs in an try and deal with situations equivalent to high blood pressure and diabetes. U.S. well being officers have warned that the compound is not efficient for treating any situation and that it might probably intrude with sure medicine, equivalent to antibiotics.
Associated: Butterfly disease: A disorder that makes skin as delicate as butterfly wings
Signs: The main symptoms of argyria are the pores and skin creating a bluish-gray or grey tint, the fingernails rising darker than regular, and darker patches showing on pores and skin in areas which can be uncovered to the solar — a situation referred to as hyperpigmentation. These colour modifications are sometimes everlasting, and sufferers with argyria might expertise psychological misery due to their look.
Signs can range relying on how a lot silver enters an individual’s physique, the way it enters the physique, and the way lengthy it has accrued. Signs might happen throughout the whole physique (generalized argyria), solely choose components of the physique (localized argyria) or particularly within the eye (argyrosis).
Argyria can even trigger different signs — equivalent to stomach ache, fatigue, complications and kidney injury — however it isn’t life-threatening. That mentioned, ingesting large amounts of silver in one go can be fatal.
Therapies: There may be at the moment no cure for argyria. Laser remedy has been examined as a method to enhance the looks of discolored pores and skin in sufferers with argyria in a number of research, with out success.
This text is for informational functions solely and isn’t meant to supply medical recommendation.