Sunday, December 21, 2025

Israel’s famed VC Jon Medved, identified with ALS, backed the tech that may enhance his life 

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Years in the past, when enterprise capitalist Jon Medved took an curiosity in backing numerous well being tech startups, he had no concept that at some point, he would want them to enhance his personal high quality of life. 

Israel tight-knit startup group obtained a blow in October when Medved, one among its most well-known VCs, introduced he was retiring instantly. He was compelled to step down from the agency he based, OurCrowd, after he was identified with the debilitating illness of Amyotrophic Lateral Sclerosis (ALS,) often known as Lou Gehrig’s illness. 

“This has come relatively sudden,” he advised TechCrunch in an audibly hoarse voice — a symptom of ALS — on what may very well be his final interview. 

“I had been feeling slightly bizarre earlier than they usually didn’t know what was ailing me,” he defined. “I used to be within the hospital for a number of weeks recovering, and that’s after they examined me and mentioned, ‘You’ve acquired ALS,’ which is a horrible illness, the worst you possibly can think about.”  

ALS is a situation that degrades the mind’s motor neurons, resulting in lack of muscle management, finally impairing strolling, speaking, consuming, and respiration. He didn’t have the basic signs, as his voice was attacked first, not his extremities, he mentioned. However he is aware of that the situation will worsen, and there’s no treatment, solely therapies. 

Medved is taken into account one of many fathers of Israel’s startup ecosystem — usually referred to as “Startup Nation” after the decades-old best-selling book of the identical identify. He helped usher it in, having moved from California to Israel in his 20s, then founding and promoting a number of tech corporations earlier than turning to investing.  

In 2013, he based OurCrowd. Whereas Israel has many powerful home-grown VC firms, in addition to branches of world companies like Bessemer, OurCrowd basically invented crowdsourced enterprise capital, the place a restricted partnership was open to any accredited investor. 

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The agency’s roster attracted LPs from Asia, Europe, the Center East and North America, rising a community of 240,000 accredited investor LPs in 195 international locations, the agency says. A lot of them are docs, attorneys, and bizarre individuals who not solely assist their funding corporations, however would have in any other case been lower out of the wealth era that VCs expertise. 

OurCrowd has backed names like Anthropic, Past Meat and Lemonade. 

Medved describes OurCrowd as now a “vital participant” backing about 500 portfolio corporations with about 74 exits, together with an exit a few weeks in the past when its infrastructure planning startup Locusview bought for $525 million digital-construction-management-for-utilities”>to Itron. 

Regardless of Israel’s battle with Gaza, which has impacted its residents and put the nation in world crosshairs over the Palestinian humanitarian disaster, its startup ecosystem has remained robust.  

Because the “startup nation,” Israel stays a key participant for tech-tested-in-gaza-wanted-by-the-west-3d9add02″>cybersecurity and protection tech in addition to AI, microchips, enterprise software program, meals tech, well being tech — the entire tech stack. For instance, in November, there was “$800 million invested within the Israeli enterprise ecosystem in a single week,” Medved mentioned. The nation now has practically 100 unicorns and over the 12 months, he estimates that between $15 billion and $16 billion was invested within the nation in enterprise offers. 

Now the tech of a few of these startups will assist him navigate life with an incurable situation. 

For example, he’s had an avatar made from himself that preserves his voice, face and mannerisms. (The photograph/video practical digital twin is pictured and the total video can be seen here.) OurCrowd AI portfolio firm D-ID, maker of brokers and avatars, partnered with voice AI startup ElevenLabs and different corporations by the ALS-focused Scott-Morgan Foundation to create an avatar system designed for folks with ALS.

He simply skilled this tech throughout a Zoom name with one other one who has ALS who was utilizing the avatar to speak. 

“So these items has grow to be very, very private to me,” Medved mentioned. “It is going to protect my voice when it goes.” 

However he mentioned there shall be a wide range of startups tech he’ll lean on. 

“We’ve made 60, 70 healthcare investments in good corporations that assist folks. We’ve acquired an organization referred to as OncoHost, which makes use of AI to assist choose what sort of immunotherapy will really be just right for you …  We now have corporations doing next-generation sequencing for the genome. We now have corporations doing power situation administration,” he catalogs. 

“I let you know now as a once-healthy individual [who took health for granted] I felt human ache and illness, however as soon as you’re really engaged in one among these nasty ailments, it modifications your perspective,” Medved shared.  

All of which means, though he’s given up his place operating the corporate and could also be retiring from the general public eye, “I’m removed from over, okay? I wish to proceed to contribute, each to OurCrowd and the general ecosystem. So I totally intend to not go off [quietly] into this good evening.” 

And ultimately, he says “I’m very proud that in a small means, though all we’re is traders, to be a part of this motion.” 

A video that includes Medved’s “digital twin” demonstrates simply how practical his avatar already is.



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